Travel Health Guide

South Africa

Few places on Earth capture the hearts of so many as South Africa. From the breathtaking natural wonders and culinary delights of Cape Town, to the cultural and historical capital of Johannesburg, and the action-packed safari on offer in Kruger National Park, this country truly has something for everyone.

Travel Health Guide

South Africa

Few places on Earth capture the hearts of so many as South Africa. From the breathtaking natural wonders and culinary delights of Cape Town, to the cultural and historical capital of Johannesburg, and the action-packed safari on offer in Kruger National Park, this country truly has something for everyone.

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(screenshot now, thank us later)

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(screenshot now, thank us later)

(screenshot now, thank us later)

(screenshot now, thank us later)

South Africa Travel Checklist

At Runway, we're looking to empower the traveler with information, resources and access to prescription travel medication. Runway Health Guides are compiled from government sources, local authorities and vetted by a team of licensed travel physicians. From vaccine requirements to medication recommendations, here’s everything you need to know.

Vaccine Entry Requirements For South Africa

Yellow Fever


If traveling directly from the US, South Africa does not require any vaccines to enter.

If your itinerary includes a visit to, or a 12+ hour layover in, a Yellow Fever endemic country prior to arrival, a Yellow Fever vaccine and proof of vaccination may be required to enter. For a list of Yellow Fever endemic countries, click here:

Countries with Risk of Yellow Fever Transmission:

African: Angola, Benin, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Republic of Cono, Cote d’Ivoire, Democratic Republic of the Congo, Equatorial Guinea, Ethiopia, Gabon, The Gambia, Ghana, Guinea, Guinea-Bissau, Kenya, Liberia, Mali, Mauritania, Niger, Nigeria, Senegal, Sierra Leone, South Sudan, Sudan, Togo, Uganda

South & Central America: Argentina, Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Panama, Paraguay, Peru, Suriname, Trinidad and Tobago, Venezuela

Proof of vaccination (Yellow Book) is only valid 10 days after you receive the vaccine.

COVID-19


Requirements for COVID-19 vaccinations change regularly. For the latest travel requirements, please refer to this interactive map developed by our friends at Sherpa.

Most travelers get these

when traveling from the US to South Africa

Vaccines

Covid 19
Childhood Vaccinations

  • Chickenpox
  • Diphtheria – Tetanus – Pertussis
  • Flu (Influenza)
  • Measles – Mumps – Rubella (MMR)
  • Polio
  • Shingles
  • Hepatitis A
  • Hepatitis B

Medications

Malaria Medication

if traveling to high transmission regions of South Africa, typically on safari, such as: Kruger National Park and surrounding private game reserves (Sabi Sands Reserve, Timbavati Game Reserve, Thornybush Private Game Reserve); regions along the Zimbabwe and Mozambique border, Limpopo, Mpumalanga, and KwaZulu-Natal Provinces. Plan ahead - you may have to start taking medication for several days before and after you travel to ensure that it is effective.

Traveler’s Diarrhea Antibiotics

to alleviate an intestinal infection resulting from eating or drinking contaminated food or water. It is the most common travel-related illness and can occur anywhere, but the highest risk destinations are in Asia, Africa, Mexico, Central and South America, and the Middle East.

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Some travelers get these

when traveling from the US to South Africa

Vaccines

Typhoid

if you are visiting rural or remote areas or enjoying an extended stay in the country.

Rabies

may be considered if planning activities that involve direct contact with animals or wildlife – ie. wild camping, cave exploring, or fieldwork in rural areas. As a rule, we recommend avoiding interaction with animals – even domestic pets may carry diseases.

Medications

Motion Sickness Medication

will ensure your travels by air, land or sea are more enjoyable without nausea and dizziness tagging along.

Sleep Aids

may be a great addition to your packing list if you struggle with jet lag or sleeplessness due to travel stress or time zone changes.

Travel Checklist

At Runway, we're looking to empower the traveler with information, resources and access to prescription travel medication. Runway Health Guides are compiled from government sources, local authorities and vetted by a team of licensed travel physicians. From vaccine requirements to medication recommendations, here’s everything you need to know.

Yellow Fever

If traveling directly from the US, South Africa does not require any vaccines to enter.

If your itinerary includes a visit to, or a 12+ hour layover in, a Yellow Fever endemic country prior to arrival, a Yellow Fever vaccine and proof of vaccination may be required to enter. For a list of Yellow Fever endemic countries, click here:

Countries with Risk of Yellow Fever Transmission:

African: Angola, Benin, Burkina Faso, Burundi, Cameroon, Central African Republic, Chad, Republic of Cono, Cote d’Ivoire, Democratic Republic of the Congo, Equatorial Guinea, Ethiopia, Gabon, The Gambia, Ghana, Guinea, Guinea-Bissau, Kenya, Liberia, Mali, Mauritania, Niger, Nigeria, Senegal, Sierra Leone, South Sudan, Sudan, Togo, Uganda

South & Central America: Argentina, Bolivia, Brazil, Colombia, Ecuador, French Guiana, Guyana, Panama, Paraguay, Peru, Suriname, Trinidad and Tobago, Venezuela

Proof of vaccination (Yellow Book) is only valid 10 days after you receive the vaccine.

COVID-19

Requirements for COVID-19 vaccinations change regularly. For the latest travel requirements, please refer to this interactive map developed by our friends at Sherpa.

when traveling from the US to South Africa

Vaccines

Covid 19
Childhood Vaccinations

  • Chickenpox
  • Diphtheria – Tetanus – Pertussis
  • Flu (Influenza)
  • Measles – Mumps – Rubella (MMR)
  • Polio
  • Shingles
  • Hepatitis A
  • Hepatitis B

Medications

Malaria Medication

if traveling to high transmission regions of South Africa, typically on safari, such as: Kruger National Park and surrounding private game reserves (Sabi Sands Reserve, Timbavati Game Reserve, Thornybush Private Game Reserve); regions along the Zimbabwe and Mozambique border, Limpopo, Mpumalanga, and KwaZulu-Natal Provinces. Plan ahead - you may have to start taking medication for several days before and after you travel to ensure that it is effective.

Traveler’s Diarrhea Antibiotics

to alleviate an intestinal infection resulting from eating or drinking contaminated food or water. It is the most common travel-related illness and can occur anywhere, but the highest risk destinations are in Asia, Africa, Mexico, Central and South America, and the Middle East.

when traveling from the US to South Africa

Vaccines

Typhoid

if you are visiting rural or remote areas or enjoying an extended stay in the country.

Rabies

may be considered if planning activities that involve direct contact with animals or wildlife – ie. wild camping, cave exploring, or fieldwork in rural areas. As a rule, we recommend avoiding interaction with animals – even domestic pets may carry diseases.

Medications

Motion Sickness Medication

will ensure your travels by air, land or sea are more enjoyable without nausea and dizziness tagging along.

Sleep Aids

may be a great addition to your packing list if you struggle with jet lag or sleeplessness due to travel stress or time zone changes.

This guide is provided for informational purposes only and does not constitute providing medical advice, nor is the information a substitute for professional medical expertise or treatment.

This guide is provided for informational purposes only and does not constitute providing medical advice, nor is the information a substitute for professional medical expertise or treatment.

This guide is provided for informational purposes only and does not constitute providing medical advice, nor is the information a substitute for professional medical expertise or treatment.

This guide is provided for informational purposes only and does not constitute providing medical advice, nor is the information a substitute for professional medical expertise or treatment.

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Treatments

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Altitude Sickness

Malaria Prevention

Traveler’s Diarrhea

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